Unusual electrophoretic patterns of plasma proteins in human subjects.

Studyof 313 plasma electrophoretic patterns from 158 hospitalized subjects revealed that 30 per cent of these patients exhibited a heterogeneity marked by occurrence of double peaks in the alpha-2 and 6 per cent in the beta globulin fraction. Occurrence of double peaks could not be related to any specific disease. Similar study of plasma from 18 normal adult subjects did not reveal double peaks in any of the protein fractions. Existenceof prealbumin components,with mobilities greater than that of the albumin, has been observedin 6 of 158 pathological subjects. Mobilities and concentrationsof componentsx1, x2, and x3 are reported.